First Enantioselective Total Synthesis of (+)‑(R)‑Pinnatolide Using an Asymmetric Domino Allylation Reaction
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An efficient total synthesis of (+)-(R)-Pinnatolide is described. As a key step an asymmetric multicomponent domino allylation reaction of methyl levulinate is used to form the quaternary stereogenic center in a highly selective way.
创建时间：
2016-02-20
