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Identification, Synthesis, and SAR of Amino Substituted Pyrido[3,2b]pryaziones as Potent and Selective PDE5 Inhibitors

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Protein Data Bank Japan2024-05-22 更新2026-03-21 收录
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Identification, Synthesis, and SAR of Amino Substituted Pyrido[3,2b]pryaziones as Potent and Selective PDE5 Inhibitors Descriptor: 5-amino-1-butyl-7-phenyl-1,6-naphthyridin-4(1H)-one, MAGNESIUM ION, ZINC ION, ... Authors: Cubbage, J.W, Brown, D.G, Jacobsen, E.J, Walker, J.K, Hughes, R.O. Deposit date: 2009-05-07 Release date: 2009-07-07 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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2009-05-07
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