EED-mediated histone methylation is critical for CNS myelination and remyelination by inhibiting WNT, BMP and senescence pathways
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
下载链接：
http://data.iscr.ac.cn/Article?id=402ce61a7fd6587f9117fb83d9c9ccfc
下载链接
链接失效反馈官方服务：
资源简介：
PRC2 catalyzes tri-methylation of histone H3 lysine residue K27 (H3K27me3), and then H3K27me3 recruits downstream regulatory factors to create a transcriptionally repressive chromatin environment. PRC2 is involved in diverse biological processes, including cell growth, cell differentiation and the maintenance of cell identity. Here, to study the role of PRC2 on oligodendrocyte myelination and remyelination, we performed RNA-seq and ATAC-seq analysis of isolated control and Eed cKO mouse OPCs.
提供机构：
Cincinnati Children's Hospital Medical Center
创建时间：
2022-02-20
