Maternal Nurtritional Programming in the Ovine Mammary Gland
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Maternal Nurtritional Programming in the Ovine Mammary Gland
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2015-07-29
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Poor maternal nutrition during gestation alters prenatal muscle growth and development in offspring. Poor maternal nutrition during gestation alters prenatal muscle growth and development in offspring
We hypothesized that poor maternal nutrition during gestation would reduce the growth and development of offspring muscle prenatally, reduce the number of myogenic progenitor cells, and result in chan
NIAID Data Ecosystem50
Skeletal muscle Nr4a1 hypomethylation and gene induction reduce insulin sensitivity in sedentary maternal high-fat offspring. Skeletal muscle Nr4a1 hypomethylation and gene induction reduce insulin sensitivity in sedentary maternal high-fat offspring
Maternal high-fat consumption has negative effects on the offspring’s obesity/diabetes susceptibility and we hypothesize that epigenetic modifications in the skeletal muscle are partly responsible for
NIAID Data Ecosystem40
Data_Sheet_1.PDF
Maternal high-fat or high-salt diets can independently program adverse cardiometabolic outcomes in offspring. However, there is a paucity of evidence examining their effects in combination on metaboli
NIAID Data Ecosystem20
MiRNA expression alternations in the offspring liver from chromium restriction diet dams
Maternal chromium restriction may disturb susceptibility in offspring. Liver from maternal chromium diet has 8 up- and 6 down- regulated miRNAs, compared to control. We performed miRNA array analyses
NIAID Data Ecosystem50
single-cell RNA-seq of cardiac tissue from offsprings of dams with different fibre intake levels
We proposed that the maternal intake of fibre could influence the epigenetic conditions in the womb, consequently altering the cardiac characteristics of the offspring. Additionally, we speculated tha
NIAID Data Ecosystem30
