Correlation between age, disease duration and severity with BPF, RNFLT and TMV.

Beta coefficients, standardized Beta coefficients, confidence interval for standardized beta coefficients and p values are provided as calculated by Generalized Estimating Equations accounting for inter-eye dependencies with age, duration, EDSS and history of optic neuritis as independent variables and RNFLT, TMV or BPF as dependent variables. For better clarity, coefficients are only given for factors that reached statistical significance. Standardized Beta was calculated as described in the Methods section. BPF = brain parenchymal fraction, RNFLT = retinal nerve fiber layer thickness, TMV = total macular volume, ON = history of optic neuritis, CI = confidence interval.