Structure of BACE complexed to compound 3a
收藏Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Structure of BACE complexed to compound 3a Descriptor: (4S)-4-(2-AMINO-6-PHENOXYQUINAZOLIN-3(4H)-YL)-N,4-DICYCLOHEXYL-N-METHYLBUTANAMIDE, Beta-secretase 1 Authors: Sharff, A.J. Deposit date: 2007-05-23 Release date: 2007-08-14 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.4 Å) Cite: 2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-Site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead. J.Med.Chem., 50, 2007
创建时间：
2007-05-23
