Prox1 determines hepatocyte versus cholangiocyte cell fate in liver progenitors

ChEBI2013-03-15 更新2026-07-21 收录

肝脏细胞命运决定

发育阶段基因调控

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Prox1 determines hepatocyte versus cholangiocyte cell fate in liver progenitors

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2013-03-15

Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development

皮质中间神经元

发育阶段基因调控

Human embryonic stem cells (hESCs) were specified as ventral telencephalic neuroectoderm (day 4) and then into medial ganglionic emininence (MGE)-like progenitors (day 15) and were subsequently differ

NIAID Data Ecosystem80

Developmental ablation of Id1 and Id3 genes in the vasculature leads to postnatal cardiac phenotypes

发育阶段基因调控

扩张型心肌病分子机制

Rationale: The Id1 and Id3 genes play major roles during cardiac development, despite their expression being confined to non-myocardial layers (endocardium – endothelium - epicardium). We previously d

NIAID Data Ecosystem30

Control of poly(A)-tail length and translation in vertebrate oocytes and early embryos

发育阶段基因调控

mRNA翻译机制研究

During oocyte maturation and early embryonic development, poly(A)-tail lengths strongly influence mRNA translation. However, how tail lengths are controlled at different developmental stages has been

NIAID Data Ecosystem20

Ancestral Regulatory Circuits Governing Ectoderm Patterning Downstream of Nodal and BMP2/4 Revealed by Gene Regulatory Network Analysis in an Echinoderm

发育阶段基因调控

海胆模式形成机制

Echinoderms, which are phylogenetically related to vertebrates and produce large numbers of transparent embryos that can be experimentally manipulated, offer many advantages for the analysis of the ge

NIAID Data Ecosystem50

Significant DEGs in MEF2C-Disrupted NSCs and iNs.

发育阶段基因调控

转录因子功能分析

Myocyte Enhancer Factor 2C (MEF2C) is a transcription factor that plays a crucial role in neurogenesis and synapse development. Genetic studies have identified MEF2C as a gene that influences cognitio

NIAID Data Ecosystem20

Prox1 determines hepatocyte versus cholangiocyte cell fate in liver progenitors

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