Functional and disease association of blood transcriptional profile in MPS IIIB mice.

Genome-wide gene expression microarrays were performed on pooled blood and brain RNA samples from 6 mo-old MPS IIIB mice and their wt littermates (n = 6/group, M:F = 1∶1). Genes of transcripts were identified by Ingenuity Pathway Analysis (IPA). *Genes associated with specific tissues according to enrichment analysis using Database for Annotation, Visualization and Integrated Discovery (DAVID); FC>2: fold change >2; **% of known genes.