The impact of methanol on behaviour: Dataset from zebrafish (Danio rerio) behavioural research
收藏DataONE2021-04-23 更新2025-05-10 收录
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In many pharmacological and toxicological studies solvents are used as vehicles for the compound of interest. The solvents themselves may have effects on their own, therefore, it is important to test the impact of the solvent on the preparation prior to conducting the study. Methanol, (CH3OH), is a solvent used in many studies, and one we have used as a vehicle for benzo[a]pyrene. This data contains raw videos of zebrafish after exposure to 0, 0.25%, or 2.5% vol/vol, for 30 minutes prior to behavioral testing. Immediately after exposure, the individual zebrafish were moved to an open field test to quantify movement and location preference and were recorded for 10 minutes. Following the open field trial, a novel object was placed into the center of the arena to examine the exploratory response (boldness) of the fish for a second 10 minute trial. Motion-tracking software (EthoVision XT) was used to quantify the dependent variables (distance moved, time in outer 'thigmotaxis' zone, 'i...
创建时间:
2025-04-30



