Treatment of human primary myotubes with PFI increases expression of several genes related to mitochondrial biogenesis, lipolysis and lipid storage.

Data are expressed as mean ± SEM of 4 separate experiments. NS: not significant. PGC-1α, peroxisome proliferator activated receptor coactivator-1 α; PPARδ, peroxisome proliferator activated receptor δ; HSL, hormone sensitive lipase; ATGL, adipose triglyceride lipase; CGI-58, comparative identification gene 58; ADRP, adipose related differentiation protein; TIP-47, tail interacting protein of 47 kDa; DGAT1, diacylglycerol acyl-transferase 1; GPAT, glycerol-3-phosphate acyl-transferase; SREBP-1, sterol responsive element binding protein-1; FASN, fatty acid synthase.