Genetic analyses reveal the signaling and transcriptional mechanisms of stomach stromal stem cell niches. [ChIP-Seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP145844
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资源简介:
We demonstrate the conserved Hh-GLI2-mediated chromatin and transcriptional regulation of both stomach and intestinal stromal stem cell niche signals. Analyses of H3K27ac marks demonstrate GLI2-mediated transcription regulation of stem cell niche signals such as Wnt ligand genes, through enhancers conserved between the stomach and intestine. Overall design: Examination of Gli2, H3K27ac, and H3K36me3-bound DNA in E17.5 Sufu;Spop double knockout mouse stomach
创建时间:
2020-01-28



