转座子可及染色质数据分析ATAC-seq
收藏资源简介:
转座子可及染色质测序分析(ATAC-Seq)用于研究基因组中的开放染色质区域。本产品包括了质控、去接头、比对参考基因组、peak的确认、转录起始位点的筛选以及对应的注释、结合转录组的数据和Chip-seq的数据进行联合分析。本产品可应用于鉴定开放染色质区域、转录因子结合位点分析、单细胞ATAC-seq。
Assay for Transposase-Accessible Chromatin sequencing (ATAC-seq) is a technique dedicated to profiling open chromatin regions in genomes. This analytical product incorporates a complete workflow including quality control, adapter trimming, alignment to the reference genome, peak calling, screening and annotation of transcription start sites (TSSs), as well as integrated analysis combined with transcriptomic data and ChIP-seq data. This product is applicable for identifying open chromatin regions, performing transcription factor binding site analysis, and supporting single-cell ATAC-seq studies.




