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A Diastereodivergent Synthetic Strategy for the Syntheses of Communesin F and Perophoramidine

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NIAID Data Ecosystem2026-03-09 收录
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An efficient, unified, and stereodivergent approach toward communesin F and perophoramidine was examined. The C(3) all-carbon quaternary center of an oxindole was smoothly constructed by base-promoted indolone-malonate alkylation chemistry. The complementary relative stereochemistry of the crucial vicinal quaternary centers found in communesin F and perophoramidine was selectively installed by substrate-controlled decarboxylative allylic alkylations.

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2015-12-17
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