5-HT2AR bound to a novel agonist in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
收藏Protein Data Bank Japan2025-05-21 更新2026-03-28 收录
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5-HT2AR bound to a novel agonist in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM) Descriptor: (3R)-3-methyl-5-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1,2,3,6-tetrahydropyridin-1-ium, 5-hydroxytryptamine receptor 2A, G protein subunit q (Gi2-mini-Gq chimera), ... Authors: Barros-Alvarez, X, Kim, K, Panova, O, Roth, B.L, Skiniotis, G. Deposit date: 2021-07-02 Release date: 2022-07-06 Last modified: 2025-05-21 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Bespoke library docking for 5-HT 2A receptor agonists with antidepressant activity. Nature, 610, 2022
创建时间：
2021-07-02
