CSE-Miner
收藏国家生物信息中心2025-10-11 更新2025-03-15 收录
下载链接：
https://cseminer.stjude.org/
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资源简介：
Immunotherapy with T-cells expressing chimeric antigen receptors (CARs) holds the promise to improve outcomes for children with solid and brain tumors. However, at present, there is a limited array of targetable antigens. We posit here that targets generated by alternative splicing events in cancer cells present an untapped class of CAR targets since many of these are tumor-specific and overexpressed in malignant cells.Thus, we developed Cancer-Specific Exon Miner (CSE-Miner), a pipeline for mining exon-based CAR-T targets
提供机构：
St. Jude Children's Research Hospital
创建时间：
2024-07-16
