TNFa-producing Macrophages Determine Subtype Identity and Prognosis via AP1 Enhancer Reprogramming in Pancreatic Cancer [cJUN-OE RNA-seq]

According to our previous data, it shows that cJUN plays an important role in regulating inflammation and basal-like phenotype in pancreatic cancer. Therefore, in this study, we wanted to use an unbiased method to investigate the global effect of cJUN in pancreatic cancer. Hence, we performed RNA-seq in GCDX62-EV cells, as well as GCDX62-cJUN cells Overall design: RNA-seq was performed in pMSCV empty vector transduced GCDX62 cells, as well as cJUN stable overexpression cells (transduced with pMSCV-cJUN plasmid). Three technical repeats were used in each group.