We undertook an integrative technological approach to compare miRNA detection capability of three high-throughput commercial platforms. Overall design: We artificially introduced human precursor, 2’-O
We provide evidence that viral miRNAs use 6mer seed toxicity to kill cells Samples of HeyA8 ovarian cancer cells transfected with different miRNAs or siRNAs
This work highlights similarities and differences between three platforms (next-generation sequencing, microarray and NanoString) for detecting miRNAs and compares their strengths and weaknesses. miRN
