A novel approach to low-cost, rapid and simultaneous colorimetric detection of multiple analytes using 3D printed microfluidic channels

This research paper presents an inventive technique to swiftly create microfluidic channels on distinct membrane papers, enabling colorimetric drug detection. Using a modified DIY RepRap 3D printer with a syringe pump, microfluidic channels (µPADs) are crafted on a flexible nylon-based substrate. This allows simultaneous detection of four common drugs with a single reagent. An optimized blend of Polydimethylsiloxane (PDMS) dissolved in hexane is used to create hydrophobic channels on various filter papers. The PDMS-hexane mixture infiltrates the paper's pores, forming hydrophobic barriers that confine liquids within the channels. These barriers are cured on the printer's hot plate, controlling channel width and preventing spreading. Capillary action drives fluid along these paths without spreading. This novel approach provides a versatile solution for rapid microfluidic channel creation on membrane papers. The DIY RepRap 3D printer integration offers precise control and faster curing. T..., The dataset was acquired utilizing AFM analysis software and a UV-VIS spectrometer, as referenced in the manuscript. Access to the Origin software is facilitated through institution., AFM Analysis software (example Gwyddion)
Origin 2016
Notepad, DATASETS INCLUDE

1. AFM CHARACTERIZATION
The Atomic Force Microscopy (AFM) data pertaining to specific membrane substrates, namely Biodyne C, Biotrace NT, and Immunodyne ABC, utilized in this study are provided. For each substrate, comprehensive AFM datasets are presented, encompassing both coated and uncoated states with polydimethylsiloxane (PDMS).

(a) The AFM data for Biodyne C membrane containing PDMS is named as (AFM_Biodyne_C_with PDMS.000) and for the Biodyne C membrane without membrane is named as (AFM_Biodyne_C_without_PDMS.000).

(b) The AFM data for Biotrace NT membrane containing PDMS is named as (AFM_Biotrace_NT_with PDMS) and for the Biodyne C membrane without membrane is named as (AFM_Biotrace_NT_without_PDMS.000).

(c) The AFM data for Immunodyne ABC membrane containing PDMS is named as (AFM_Immunodyne_ABC_With PDMS) and for the Biodyne C membrane without membrane is named as (AFM_Immunodyne_ABC_without_PDMS.000).

Enclosed within this resource are the unprocessed...