In vivo CRISPR screens for Toxoplasma using metabolism sublibrary in WT and Ifngr1-deficient mice
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https://www.ncbi.nlm.nih.gov/sra/SRP432299
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资源简介:
We performed in vivo CRISPR screen of Toxoplasma targeting metabolism-related genes to identify in vivo fitness genes in WT and Ifngr1-deficient mice. Overall design: This sublibrary targeting 361 genes which consisted 3610 gRNAs targeting metabolism-related genes together with dispensable and essential control genes. We performed in vivo CRISPR screens to identify novel virulence factors of Toxoplasma.
创建时间:
2023-06-13



