Hif-1alpha deletion leads to adverse treatment efficacy in a mouse model of MLL-AF9 driven AML
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=b6595b1700ba63134f56ca8f937880fb
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资源简介：
This report explores the effect of Hif-1alpha deletion, using a conditional mouse model, together with standard chemotherapy regimen to evaluate leukemia stem cell (LSC) targeting in a murine model of MLL-AF9 driven acute myeloid leukemia (AML). This study reveals that Hif-1alpha-deleted leukemias displayed a faster disease progression after chemotherapy.
提供机构：
BMC
创建时间：
2022-02-20
