Western blot screening of the 20 drugs and optimization at different times in JHU029, HTB-43 and CCL-138 (parental and resistant) cell lines. Treatment was tested at 8, 24 and 48 hours and the drug 13
Protein lysates were collected from A549 and HEKT293T ishXrn1 cells treated with doxycycline for 3-4 days or left untreated. They were then probed with antibodies against Xrn1 or beta-tubulin as a