Crystal structure of IRE1 in complex with G-3053
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Crystal structure of IRE1 in complex with G-3053 Descriptor: 4-[(trans-4-aminocyclohexyl)amino]-N-(6-chloro-3-{[(2,5-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)thieno[3,2-d]pyrimidine-7-carboxamide, Serine/threonine-protein kinase/endoribonuclease IRE1 Authors: Ackerly-Wallweber, H, Wang, W. Deposit date: 2020-06-10 Release date: 2021-04-21 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1 alpha Inhibitory Activity. Acs Med.Chem.Lett., 11, 2020
创建时间：
2020-06-10
