Sample viral load and number of LLV sequences/samplea
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aThe number of sequences generated in each plasma sample is shown to the left of the sample's viral load which is denoted in parentheses.bViral load (VL) was determined by our standard viral load assay which has a sensitivity of 50 vRNA copies/mL.cTime points where some LLV sequences contained mutations which were not observed in the pre-suppression profiledSamples were obtained at necropsy and approximately 20 mL of plasma was analyzed to generate LLV sequences.eViral load determined by an unmodified ultracentrifugation viral load assay (Deere et al.[48] using triplicate 10 µL vRNA samples. Sensitivity was 2 vRNA copies/mL.
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2015-12-02
