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Effects of Conditional Egfr deletion on transcriptome of the mouse cerebral cortex

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To investigate the role of Egfr in the cerebral cortex and hippocampal formation we conditionally deleted it using a floxed allele in combination with the Nestin-cre transgene. Cortices at E17.5 embryonic stage were harvested and split into rostral and caudal halves and RNA extracted and sequenced Comparison of RNA-seq data between rostral and caudal cortices and hippocampal formation of control brains (EgfrF/+ genotype) and brain-specific knock of Egfr (Nestin-EgfrF/F).

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