five

The lncRNA locus Handsdown regulates cardiac gene programs and is essential for early mouse development

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NIAID Data Ecosystem2026-04-25 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP150058
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WT and Handsdown mutant ESC were differentatied into the meosdermal cell lineage and harvested at desiganted timepoints für differential expression profiling (n=3). Hearts of E9.5 mouse embryos were harvested and profiled to generate a represantative picture of RNAs (n=1). 4C-seq analysis of mESCs, cardiomyocytes and whole hearts from E11.5 mouse embryos Overall design: Examination of 2 differnet chromatin states and RNA expression in 2 different Brachyury mutants embryos of in vitro differentiated mouse embryonic stem cells 4C-seq with the promoter region of Handsdown as the viewpoint
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2019-11-19
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