Serum microRNA profile of human type 1 diabetes mellitus. Homo sapiens

To evaluate whether serum micoRNAs can be biomarkers for diagnosis of type 1 diabetes mellitus, we analyzed the serum microRNA expression profiles in 6 patients with new-onset type 1 diabetes mellitus and 6 age- and gender-matched healthy controls. A difference was observed in 31 miRNAs between the patients and controls (fold change ≥ 2, P < 0.05) Overall design: 6 serum samples from patients with new-onset type 1 diabetes mellitus and 6 serum samples from age- and gender-matched healthy controls