Werner syndrome diagnostic criteria.

*WS signs and symptoms are from the diagnostic criteria established by the International Registry of Werner Syndrome: www.wernersyndrome.org/registry/diagnostic.html.
**Reported cataracts were assumed bilateral if not explicitly stated, and characteristic dermatological pathology was considered to be present if any one of the six skin pathologies was reported, again as defined by the Werner Syndrome Registry diagnostic signs and symptoms list. Where height was not designated as ‘short stature’, we classified males with heights <164 cm and females with heights <154 cm as of short stature. Diabetes mellitus was considered present if a diagnosis of diabetes and/or evidence of abnormal glucose homeostasis was provided.