Longitudinal association of change in BMI with the mental and physical SF-12 summary scores during the 3-year follow-up, stratified by sex and BMI category.

Abbreviations: BMI = body mass index, CI = confidence intervals, SF = Short Form.1Stratified regression coefficients are reported only in the case of significant interaction terms in the basic model (P2β can be interpreted as the change in SF-12 summary score per increase in BMI change of 1 kg/m2 over time.3Basic model included the SF-12 summary score at all time points as the dependent variable and baseline BMI, change in BMI from baseline to all follow-up points, age, sex, study arm, interaction term time × study arm, and time-dependent smoking status as independent variables, n = 6726.4Further adjusted model consisting of the basic model additionally adjusted for education level, employment status, living situation, diagnosis of diabetes and hypertension, and history and time-dependent cumulative incidence of myocardial infarction/stroke and coronary artery bypass grafting/percutaneous coronary intervention within the previous 6 months, n = 6682.5Normal weight (BMI 18.5 to 2), overweight (BMI 25 to 2), and obese (BMI ≥30 kg/m2).