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资源简介：
The goal is to test the potency of our LNPs for Cas9 mRNA/gRNA delivery.
应用场景：
创建时间：
2024-01-24
相关数据集
Crystal structure of xCas9 P411T
Crystal structure of xCas9 P411T Descriptor: CRISPR-associated endonuclease Cas9/Csn1 Authors: Bao, R, Liu, H.Y, Luo, Y.Z, Song, Y.J. Deposit date: 2021-09-29 Release date: 2022-04-06 Last modified: 2
Protein Data Bank Japan2023-11-29 更新50
Retroelement insertion in a CRISPR/Cas9 editing site in the early embryo intensifies genetic mosaicism. Retroelement insertion in a CRISPR/Cas9 editing site in the early embryo intensifies genetic mosaicism
Continued CRISPR/Cas9-mediated editing activity that allows differential and asynchronous modification of alleles in successive cell generations expands allelic complexity. To understand the earliest
NIAID Data Ecosystem50
Decorating chromatin for enhanced genome editing using CRISPR-Cas9
To improve the efficiency of homology-directed repair of double-stranded breaks introduced by CRISPR-Cas9, a Cas9-PRDM9 (PR/SET Domain 9) fusion protein was generated and tested in HEK-293T cells. RNA
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Applications of artificial intelligence to lipid nanoparticle delivery
Lipid nanoparticles (LNPs) are nanocarriers composed of four lipid components and can be used for gene therapy, protein replacement, and vaccine development. However, LNPs also face several challenges
DataCite Commons2025-04-27 更新50
Single-cell transcriptomes and runx2b-/- mutants reveal the genetic signatures of intermuscular bone formation in teleosts
Purpose: Intermuscular bones (IBs) are hard spicules, mainly existing in the myosepta of recent vertebrates. This evolutionary trait has puzzled biologists and consumers, and the molecular basis of IB
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