The intrinsically disordered region of SPIN1 regulates its function by phase separation.

NIAID Data Ecosystem2026-05-02 收录

蛋白质相分离

内在无序区域功能

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE215400 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2024-12-20

[Dataset] Comprehensive protein datasets and benchmarking for liquid-liquid phase separation studies

蛋白质相分离

生物信息学基准

Proteins self-organize in dynamic cellular environments by assembling into reversible biomolecular condensates through liquid-liquid phase separation (LLPS). These condensates can comprise single or m

DataCite Commons2025-07-28 更新70

High-content imaging, immunoblot and immunofluorescence data related to: Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH

蛋白质相分离

细胞应激颗粒调控

G3BP is the central node within stress-induced protein–RNA interaction networks known as stress granules (SGs). The SG-associated proteins Caprin-1 and USP10 bind mutually exclusively to the NTF2 doma

NIAID Data Ecosystem40

Phase separation of PGL-3 driven by structured domains that oligomerize and interact with RGG motifs

蛋白质相分离

生物分子凝聚体

Phase separation (PS) of biomolecular condensates is often assumed to be driven by interactions 2 involving nucleic acids and intrinsically disordered regions (IDRs) of proteins. PGL-3 is a 3 componen

NIAID Data Ecosystem10

Table S2. Overview on active zone proteins (full table, supplementary to Figure 2) from Protein phase separation hot-spots at the presynapse

蛋白质相分离

突触蛋白质组学

Protein characteristics include intrinsic disorder (Av â€“ Average, line profile along the full protein sequence), low complexity (# - number of residues, percentage of protein length) and percentage

NIAID Data Ecosystem50

Nuclear Condensation of NUP98-Fusion Proteins drives leukemogenic gene expression

白血病分子机制

蛋白质相分离

NUP98-fusion proteins cause acute myeloid leukemia via unknown molecular mechanisms. All NUP98-fusion proteins share an intrinsically disordered region (IDR) featuring >35 repeats of Phenylalanine-Gly

NIAID Data Ecosystem10

The intrinsically disordered region of SPIN1 regulates its function by phase separation.

资源简介：

相关数据集