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Mapping translocation breakpoint using Solexa sequencing

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NIAID Data Ecosystem2026-03-07 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP000102
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We have performed shotgun sequencing of flow-sorted derivative chromosomes using next generation (Solexa/Illumina) multiplex sequencing-by-synthesis technology. As shown here for three different disease-associated BCRs, the coverage attained by this platform is sufficient to bridge the breakpoints by PCR amplification, and this procedure allows to determine their exact nucleotide positions within few weeks
创建时间:
2013-08-23
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