BACKGROUND: Intestinal bacteria are known to regulate the bile acid (BA) homeostasis via intestinal biotransformation of BAs and stimulating the expression of fibroblast growth factor 19 through intes

NIAID Data Ecosystem20

Raw data used for stduying interaction between bile acid and gut microbiome. Human fecal samples

胆汁酸-微生物组互作

肝病相关微生物组

Human fecal samples from hydatid patients, liver cirrhosis patients, and healthy controls (shortgun). Paired oral and fecal samples from patients with hydatid disease and cirrhosis (full-length 16S).

NIAID Data Ecosystem10

Table 2_MASH and the race for liver antifibrotics.pdf

纤维化治疗

代谢性肝病药物研发

Metabolic dysfunction-associated steatohepatitis (MASH), along with other chronic liver diseases, leads to progressive fibrosis and, ultimately, cirrhosis. Liver fibrosis is a major cause of global mo

NIAID Data Ecosystem20

Exploring bile acids changes and microflora profile in chicken fatty liver disease model

家禽脂肪肝病模型

胆汁酸-微生物组互作

This study unveils bile acid and microflora changes in a chicken NAFLD model, enhancing our understanding of fatty liver disease metabolism and aiding targeted interventions.

科学数据银行2023-09-13 更新10

Unlocking therapeutic potential of amlexanox in MASH with insights into bile acid metabolism and microbiome

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