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Genetic Screen Identifies MicroRNA Cluster 99b/let-7e/125a as a Regulator of Primitive Hematopoietic Cells

ChEBI2011-12-15 更新2026-07-21 收录

造血干细胞调控

微小RNA

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-33691 数据链接链接失效反馈

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资源简介：

Genetic Screen Identifies MicroRNA Cluster 99b/let-7e/125a as a Regulator of Primitive Hematopoietic Cells

应用场景：

创建时间：

2011-12-15

微小RNA

基因调控

MicroRNAs (miRNAs) are critical to proliferation, differentiation, and development. Here, we characterize gene expression in murine Dicer-null adult mesenchymal stem cell lines, a fibroblast cell type

干细胞与再生医学数据中心2022-02-20 更新130

ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation

造血干细胞调控

转录因子功能分析

To investigate the role of the transcription factor ERG in hematopoiesis we generated Erg heterozygous knockout and conditional Erg knockout mice. We found that several hematopoietic cell types were d

NIAID Data Ecosystem60

An integrated global regulatory network of hematopoietic precursor cell self-renewal and differentiation. Mus musculus

造血干细胞调控

细胞命运决定

The mammalian blood system is a hierarchically structured tissue. Hematopoietic stem cells (HSC) reside at the top of this hierarchy and the HSC-derived progenitor cells (HPC) have capacities for both

NIAID Data Ecosystem30

small RNA sequencing of cellular secretome

微小RNA

细胞器间通讯

small RNA sequencing of HEK293T and hTERT-MSC secretome and cells

NIAID Data Ecosystem80

Additional file 4: Table S4. of miR-27b shapes the presynaptic transcriptome and influences neurotransmission by silencing the polycomb group protein Bmi1

神经元突触转录组学

微小RNA

Comparative analysis of the presynaptic transcriptome in miR-27b KD neurons by nCounter or microarray profiling. (XLSX 11Â kb)

Figshare2016-12-14 更新50