Additional file 16: of Cytolytic activity correlates with the mutational burden and deregulated expression of immune checkpoints in colorectal cancer

Table S7. GISTIC (v2.0.22) analysis results for colon cancers (COAD). GISTIC was used to detect recurrent somatic copy number alterations (SCNA) in CYT-high and -low colon cancers, using MutSigCV (v1) from the Broad Institute’s GenePattern. Each SCNA was assigned a G-score indicative of its amplitude and occurrence across samples. SCNAs in each COAD sample within each cytolytic subgroup were counted by taking the sum of segment mean changes ≥ 0.6 and ≤ − 0.4 between somatic and normal samples. Significantly amplified or deleted genomic regions in each cytolytic subgroup with FDR < 0.25 were considered significant. (XLSX 95 kb)