Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 8
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Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 8 Descriptor: (3R,4S)-N-(4-{TRANS-2-[4-(2-FLUORO-6-HYDROXY-3-METHOXY-BENZOYL)-PHENYL]-VINYL}-AZEPAN-3-YL)-ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... Authors: Breitenlechner, C.B, Wegge, T, Berillon, L, Graul, K, Marzenell, K, Friebe, W.G, Thomas, U, Schumacher, R, Huber, R, Engh, R.A, Masjost, B. Deposit date: 2004-03-29 Release date: 2005-03-29 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-based optimization of novel azepane derivatives as PKB inhibitors J.Med.Chem., 47, 2004
创建时间:
2004-03-29



