Dual checkpoint blockade of CD47 and PD-L1 using a novel affinity-tuned bispecific antibody maximizes anti-tumor immunity

NIAID Data Ecosystem2026-03-13 收录

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双特异性抗体

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE180297 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2022-04-22

4-1BB Co-stimulation Further Enhances Anti-PD-1-Mediated Reinvigoration of Exhausted CD39+ CD8 T Cells from Primary and Metastatic sites of Epithelial Ovarian Cancers. 4-1BB Co-stimulation Further Enhances Anti-PD-1-Mediated Reinvigoration of Exhausted CD39+ CD8 T Cells from Primary and Metastatic sites of Epithelial Ovarian Cancers

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T细胞功能分析

4-1BB Co-stimulation Further Enhances Anti-PD-1-Mediated Reinvigoration of Exhausted CD39+ CD8 T Cells from Primary and Metastatic sites of Epithelial Ovarian Cancers Overall design: Compare gene expr

NIAID Data Ecosystem20

Type I interferon signaling pathway enhances immune-checkpoint inhibition in KRAS mutant lung tumors [cell lines]

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KRAS突变肺癌

Lung cancer is the leading cause of cancer mortality worldwide. KRAS oncogenes are responsible for at least a quarter of lung adenocarcinomas, the main subtype of lung cancer. After four decades of in

NIAID Data Ecosystem10

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免疫检查点

This record contains data related to article "NKG2A expression identifies a subset of human Vδ2 T cells exerting the highest antitumor effector functions" Human Vδ2 cells are innate-like γδ T effector

Zenodo2022-02-09 更新10

Characterization of Natural Killer Cell Sensitivity of Circulating Tumor Cells in Non-small Cell Lung Cancer using Bulk RNA-sequencing. Characterization of Natural Killer Cell Sensitivity of Circulating Tumor Cells in Non-small Cell Lung Cancer using Bulk RNA-sequencing

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NK细胞毒性

To investigate whether circulating tumor cells exhibit NK sensitive gene expression profiles, we performed bulk RNA-sequencing on NK sensitive and NK resisitant cell lines, including two in-house deri

NIAID Data Ecosystem10

Additional file 2 of Lung cancer cell-intrinsic IL-15 promotes cell migration and sensitizes murine lung tumors to anti-PD-L1 therapy

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癌细胞迁移

Supplementary Material 2

Figshare2024-08-18 更新10