Crystal structure of TrkA in complex with PF-06273340
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Crystal structure of TrkA in complex with PF-06273340 Descriptor: High affinity nerve growth factor receptor, N-{5-[2-amino-7-(1-hydroxy-2-methylpropan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl}-2-(5-chloropyridin-2-yl)acetamide Authors: Jayasankar, J, Kurumbail, R, Skerratt, S, Brown, D. Deposit date: 2016-04-19 Release date: 2017-03-01 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.63 Å) Cite: The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain. J. Med. Chem., 59, 2016
创建时间：
2016-04-19
