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Gene expression analysis of OX40+ Tregs from human liver tissues

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE103523
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Analysis of the gene signature of OX40+ Tregs, in comparison to OX40- Tregs and Tconvs, freshly isolated from liver cirrhosis and tumor of chronic HCV patients. Results provide insights into the metabolic mechanisms of Treg proliferation in premalignant/malignant contexts. Total RNA extracted from OX40+ or OX40- Tregs or Tconvs, obtained from peripheral blood or from fragments of cirrhotic and tumor (hepatocellular carcinoma) liver tissue. Samples from 5 chronic HCV patients (4M+1F, aged 53-80 years) were pooled.
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2021-07-25
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