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Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

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NIAID Data Ecosystem2026-03-07 收录
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https://www.omicsdi.org/dataset/ega/EGAS00000000054
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We have used next generation sequencing to sequence genomes (>43-fold coverage) and transcriptomes of an oestrogen-receptor-alpha-positive metastatic lobular breast cancer at depth. We found 32 somatic non-synonymous coding mutations present in the metastasis, and measured the frequency of these somatic mutations in DNA from the primary tumour of the same patient. EGA study EGAS00000000054
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2013-05-22
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