Figure S1 - PB1-F2 Attenuates Virulence of Highly Pathogenic Avian H5N1 Influenza Virus in Chickens

Virus isolation by plaque assay on MDCK cells from oral swabs of chickens infected with 1000 PFU collected at 2 dpi (wt n = 15; ΔF2 n = 15) and at 4 dpi (wt n = 7; ΔF2 n = 5). No live virus could be detected in swabs from 6 chickens in the wt-infected condition at day 2 pi, and from 9 chickens in the ΔF2-infected condition at day 2 pi. (PDF)