Advances in genetics and sequencing have lead to a deluge of disease-associated and disease-causing genetic alterations. Resolving causality between genetics and disease requires generating accurate m
single cell RNA-seq/CITE-seq analysis of bone marrow cells from wild type and Kmt2c-deleted mice Overall design: Lin-Kit+ cells were isolated, stained with barcoded antibodies and processed with 10x g
The aim of this study was to characterize in vivo miRNA expression in normal myeloid development of the neutrophil granulocyte (granulopoiesis) to gain insight into miRNA control of these processes. C
GM-CSF controls the development of granulocytes but little is known about the contribution of the downstream mediating transcription factor STAT5A/B. To elucidate this pathway, we generated mice lack