Crystal structure of human PTPN2 with inhibitor ABBV-CLS-484
收藏Protein Data Bank Japan2026-03-04 更新2026-04-19 收录
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Crystal structure of human PTPN2 with inhibitor ABBV-CLS-484 Descriptor: 5-{(7R)-1-fluoro-3-hydroxy-7-[(3-methylbutyl)amino]-5,6,7,8-tetrahydronaphthalen-2-yl}-1lambda~6~,2,5-thiadiazolidine-1,1,3-trione, Tyrosine-protein phosphatase non-receptor type 2 Authors: Longenecker, K.L, Qiu, W, Sun, Q, Frost, J.M. Deposit date: 2022-03-12 Release date: 2023-07-26 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.044 Å) Cite: The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity. Nature, 622, 2023
创建时间：
2022-03-12
