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EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling

ChEBI2015-09-14 更新2026-07-12 收录

胶质母细胞瘤分子机制

EGFR基因表达调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-72468 数据链接链接失效反馈

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EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling

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创建时间：

2015-09-14

胶质母细胞瘤分子机制

单细胞RNA测序药物研究

Aryl hydrocarbon receptor (AhR) is a ligand-activated and cancer releated transcription factor. 2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE) is an AhR ligand, which regulat

NIAID Data Ecosystem50

SETD2 Palmitoylation Mediated by ZDHHC16 in Epidermal Growth Factor Receptor-Mutated Glioblastoma Promotes Ionizing Radiation-Induced DNA Damage

胶质母细胞瘤分子机制

靶向治疗研究

Purpose: The prevalence of epidermal growth factor receptor (EGFR) mutations in glioblastoma multiforme (GBM) has elicited a significant focus on EGFR as a potential drug target. However, no significa

科学数据银行2023-09-11 更新30

Gene expression profiles of PTPRZ1-knocking-down human glioblastoma stem cells [PrimeView]

胶质母细胞瘤分子机制

基因表达谱分析

Gene expression profiles of PTPRZ1-knocking-down human glioblastoma stem cells [PrimeView]

ChEBI2015-05-21 更新30

Additional file 12 of Decoding key cell sub-populations and molecular alterations in glioblastoma at recurrence by single-cell analysis

胶质母细胞瘤分子机制

细胞基因调控网络

Additional file 12. Table S7. The intersection of rGBM GS genes and MAFK targets from ChIP-Atlas.

Figshare2023-07-31 更新40

Supplementary Table S5 from Combined Inactivation of MEK and mTOR Can Lead to Synergistic Cell Death in Glioblastoma Models and Associates with NF1 Deficiency and a Mesenchymal Subtype