Crystal structure of MAP4K1 with a SMOL inhibitor
收藏Protein Data Bank Japan2025-01-29 更新2026-04-19 收录
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Crystal structure of MAP4K1 with a SMOL inhibitor Descriptor: Mitogen-activated protein kinase kinase kinase kinase 1, [(5~{R})-2-[[3,5-bis(fluoranyl)-4-[[3-(trifluoromethyl)-1~{H}-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]amino]-5-fluoranyl-4,6-dihydro-1,3-oxazin-5-yl]methanol Authors: Friberg, A. Deposit date: 2023-06-08 Release date: 2024-06-26 Last modified: 2025-01-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T-Cell Immunity against Cancer. J.Med.Chem., 67, 2024
创建时间：
2023-06-08
