Tissue-specific insulin resistance indices and fasting plasma insulin as predictors of total incident CVD events in the 5.9-Years METSIM prospective study, Kuopio, Finland.

Abbreviations: CI, confidence interval; CVD, cardiovascular disease; HR, hazard ratio; IR, insulin resistance; LDL-C low-density lipoprotein cholesterol.
Cox regression analysis. HRs were calculated using standardized predictors (unit = one standard deviation). Individuals with previously or newly diagnosed type 2 diabetes and type 1 diabetes at baseline were excluded from the analyses, as well as individuals with myocardial infarction and stroke before the baseline. Bold font indicates statistical significance P<0.0125. Individuals with type 1 diabetes (N = 25), type 2 diabetes (N = 763) or newly diagnosed type 2 diabetes at baseline (N = 649) were excluded.
P, unadjusted.
Pa, adjusted for age, BMI smoking, physical activity, alcohol consumption and family history of type 2 diabetes, hypertension (diagnosis was based on drug reimbursement) and LDL-C at baseline.
*Matsuda IR was calculated as: 10/Matsuda ISI.
Tissue-specific insulin resistance indices and fasting plasma insulin as predictors of total incident CVD events in the 5.9-Years METSIM prospective study, Kuopio, Finland.