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KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs

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NIAID Data Ecosystem2026-03-14 收录
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To gain a deeper insight into roles of MECP2 in hESCs derived organoids, we performed RNA-seq to analyze the transcriptome changes after MECP2 deletion in hESCs-derived organoids. Overall design: Total RNA was extracted from WT and MECP2-KO organoids treated after KW-2449 or VPA,and generated by deep sequencing, in two biological replicates, using novaseq 6000.

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2023-01-09
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