Crystal structure of the first bromodomain of human BRD4 with benzotriazolo-diazepine scaffold
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Crystal structure of the first bromodomain of human BRD4 with benzotriazolo-diazepine scaffold Descriptor: 5-[(4S)-6-(4-chlorophenyl)-1,4-dimethyl-5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-8-yl]pyridin-2-amine, Bromodomain-containing protein 4 Authors: Setser, J.W, Poy, F, Tang, Y, Bellon, S.F. Deposit date: 2015-03-27 Release date: 2015-04-08 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (1.06 Å) Cite: Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains. Acs Med.Chem.Lett., 7, 2016
创建时间：
2015-03-27
