AAV Delivery of intein-split base editors
收藏NIAID Data Ecosystem2026-04-25 收录
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资源简介：
These data were generated by a series of experiments designed to optimized and validate base editing in vivo. We used protein inteins to split and deliver base editors, which are too large to be delivered by AAV in their intact form. Base editing (Komor et al., 2016; Gaudelli 2017) mediates single-base substitutions in DNA, which could treat many genetic diseases caused by point mutations.
创建时间：
2020-01-12
