SHP2 in complex with a novel allosteric inhibitor
收藏Protein Data Bank Japan2024-06-19 更新2026-03-28 收录
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SHP2 in complex with a novel allosteric inhibitor Descriptor: Tyrosine-protein phosphatase non-receptor type 11, [(1~{S},6~{R},7~{S})-3-[3-[2,3-bis(chloranyl)phenyl]-2~{H}-pyrazolo[3,4-b]pyrazin-6-yl]-7-(4-methyl-1,3-thiazol-2-yl)-3-azabicyclo[4.1.0]heptan-7-yl]methanamine Authors: di Fabio, R, Petrocchi, A. Deposit date: 2023-01-25 Release date: 2023-04-26 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric Inhibitors. Acs Med.Chem.Lett., 14, 2023
创建时间：
2023-01-25
