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Crystal structure of dihydroorotase in complex with plumbagin from Saccharomyces cerevisiae

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Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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Crystal structure of dihydroorotase in complex with plumbagin from Saccharomyces cerevisiae Descriptor: (2S)-2-hydroxybutanedioic acid, 5-hydroxy-2-methylnaphthalene-1,4-dione, Dihydroorotase, ... Authors: Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. Deposit date: 2020-06-08 Release date: 2021-06-09 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Plumbagin, a Natural Product with Potent Anticancer Activities, Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine Biosynthesis. Int J Mol Sci, 22, 2021
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2020-06-08
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